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KMID : 1134820110400101371
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Journal of the Korean Society of Food Science and Nutrition
2011 Volume.40 No. 10 p.1371 ~ p.1377
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Antioxidative Effects of Solvent Fractions from Nandina domestica Fruits
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Seo Soo-Jung
Shim Kyu-Bong
Kim Nam-Woo
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Abstract
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This study was carried out to compare the antioxidative effects of various Nandina domestica fruits extracts. Organic fractions, including n-hexane, chloroform, ethyl acetate, and butanol fractions, were obtained from the water and ethanol extracts of N. domestica fruits. The phenolic compound content of the EE fraction was 922.22 mg/g. The flavonoid compound content was highest in the EB fraction (282.49 mg/g). The electron-donating ability was highest (93%) in the WA and EH fractions at 0.1 mg/mL. The SOD-like activity was showed the highest in the EA fraction (56.36%), and EH and EC both showed higher than 50% activity. The nitrite-scavenging ability of the EC fraction at 1.0 mg/mL under pH 1.2 conditions was 82.03%. The xanthine oxidase inhibitory activities of all the fractions, except WE, were higher than 90% at 0.5 mg/mL. The effect of tyrosinase inhibition was highest in the WE fraction (46.75%). These results show that the N. domestica fruits fractions contained high levels of polyphenol and flavonoid compounds, along with excellent antioxidative effects. This suggests that N. domestica fruits can be used as a functional material.
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KEYWORD
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N. domestica, solvent fraction, antioxidative effect, electron donating, xanthine oxidase inhibition
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